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Microscopic or macroscopic degenerative changes or abnormalities in infected host cells and tissues are called __________ __________.

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Viroids are:


A) proteins that may infect man and other animals causing spongiform encephalopathy.
B) a class of so-called slow viruses.
C) a new class of small single stranded DNA viruses that infect some animals.
D) short infectious single stranded RNAs that can infect some plants.

E) A) and B)
F) A) and C)

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The protein coat surrounding the viral genome is called the


A) capsule.
B) capsid.
C) matrix.
D) envelope.

E) C) and D)
F) None of the above

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Viruses have typical cellular structure like other living organisms.

A) True
B) False

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Adult T-cell leukemia is thought to be caused by


A) herpesviruses.
B) retroviruses.
C) parvoviruses.
D) picornaviruses.

E) All of the above
F) A) and D)

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Which of the following represent(s) the way(s) in which enveloped viruses acquire their envelopes?


A) budding through the plasma membrane.
B) budding through internal cellular membranes.
C) Viral enzymes are responsible for production of the envelope.
D) For some viruses, a is correct; for other viruses, b is correct.

E) A) and B)
F) A) and C)

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Viroids are of economic significance because they cause disease in


A) plants.
B) animals.
C) humans.
D) all of the choices

E) B) and C)
F) B) and D)

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Almost all known plant viruses are RNA viruses.

A) True
B) False

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__________ are glycoprotein spikes protruding from the outer surface of the viral envelope.

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Two major types of symmetry found in viruses include


A) icosahedral and radial.
B) icosahedral and helical.
C) helical and radial.
D) radial and bilateral.

E) All of the above
F) A) and B)

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Viral capsids are generally constructed without any outside aid once the subunits have been synthesized. This process is called


A) facilitated assembly.
B) self-assembly.
C) spontaneous maturation.
D) self-maturation.

E) A) and B)
F) A) and C)

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Which of the following is not a mechanism by which viruses cause cancer?


A) They carry a cancer-causing gene into the cell.
B) They encode proteins that bind to and inactivate host cell proteins known as tumor suppressor proteins.
C) They produce defective interfering particles.
D) An expression of viral proteins results in abnormal expression of genes that regulate cell growth and reproduction.

E) A) and B)
F) A) and D)

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Icosahedral viruses are constructed from ring- or knob-shaped units called __________.

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Which of the following is most true of a viral DNA genome?


A) It uses the same four nitrogenous bases found in prokaryotic and eukaryotic DNA.
B) It may have the normal bases found in prokaryotic and eukaryotic DNA, or it may have one or more unusual bases.
C) It is usually composed of unusual bases unique to viruses.
D) Viruses do not use DNA for their genome.

E) A) and C)
F) None of the above

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One way in which small viruses package more information into a very small genome is to use overlapping genes so that the same base sequence is read in more than one reading frame.

A) True
B) False

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Viruses infecting protists, including algae, have never been detected.

A) True
B) False

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False

Virus receptors are often not distributed uniformly over the surface of host cells, but are instead concentrated in lipid rafts.

A) True
B) False

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Virus morphology does not include which of the following characteristics?


A) size
B) shape
C) presence or absence of an envelope
D) host range

E) B) and C)
F) A) and D)

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Enveloped viruses may enter their host cells by engulfment within coated vesicles (endocytosis).

A) True
B) False

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True

Prions are of significance because they cause infections of


A) domestic animals and humans.
B) plants.
C) fungi.
D) prokaryotes.

E) A) and D)
F) A) and C)

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A

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