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Activation of lymphocytes occurs in


A) primary lymphatic structures.
B) secondary lymphatic structures.
C) tertiary lymphatic structures.
D) effectors such as muscles and glands.

E) None of the above
F) All of the above

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Once a helper T-lymphocyte recognizes an antigen, it begins the immune response by secreting chemical signals called


A) antibodies.
B) immunoglobulins.
C) memory B-lymphocytes.
D) memory T-lymphocytes.
E) cytokines.

F) A) and D)
G) B) and D)

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Cytotoxic T-lymphocytes that have killed a foreign cell may transform into


A) memory B-lymphocytes.
B) natural killer cells.
C) plasma cells.
D) helper T-lymphocytes.
E) None of the choices is correct.

F) C) and D)
G) D) and E)

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Proteins known as ________ are produced by a variety of cells; they increase capillary permeability, increase CAM production in the endothelium, and stimulate pain receptors.

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The constant region of the five classes of immunoglobulins are the same, and their names depend on their variable regions.

A) True
B) False

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Lymphocytes don't stay in one lymphatic structure for long, which ensures better chances of meeting their antigen. This process of lymphocytes re-entering the blood and lymph to circulate every few days is called lymphocyte ________.

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A virus is ______ than a bacterial cell, and a virus is composed of ________.


A) larger; nucleic acid within a protein capsid.
B) larger; a eukaryotic cell with a cell wall.
C) smaller; nucleic acid within a protein capsid.
D) smaller; a eukaryotic cell with a cell wall.

E) C) and D)
F) B) and D)

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When compared to a primary response, the antibody levels in a secondary response


A) rise more rapidly and with a greater proportion of IgG antibodies.
B) rise more rapidly and with a smaller proportion of IgG antibodies.
C) rise more gradually and with a greater proportion of IgG antibodies.
D) rise more gradually and with a smaller proportion of IgG antibodies.

E) C) and D)
F) A) and D)

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Which cells resemble basophils and are found in connective tissue, close to small blood vessels?


A) Dendritic cells
B) Mast cells
C) NK cells
D) Alveolar macrophages
E) Cytokines

F) B) and C)
G) A) and E)

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In terms of their chemical structure, cytokines are ________; their function is to serve as ________.


A) proteins; chemical messengers
B) proteins; receptors
C) steroids; chemical messengers.
D) steroids; receptors.

E) None of the above
F) B) and C)

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The most prevalent antibody in blood and lymph is


A) IgA.
B) IgC.
C) IgD.
D) IgE.
E) IgG.

F) A) and B)
G) A) and C)

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Erythrocytes are antigen-presenting cells.

A) True
B) False

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Antigen presentation involves the display of an antigen


A) inside the cytoplasm of a B-lymphocyte.
B) on the surface of a cell so that a B-lymphocyte can be exposed to it.
C) inside the cytoplasm of a T-lymphocyte.
D) on the surface of a cell so that a T-lymphocyte can be exposed to it.

E) B) and C)
F) C) and D)

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Which type of cell is the most effective to attack multicellular parasites such as tapeworms?


A) Basophils
B) Eosinophils
C) Macrophages
D) Neutrophils

E) B) and C)
F) A) and B)

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IgA is primarily found


A) in blood.
B) in external secretions such as tears, saliva, and mucus.
C) in lymph.
D) on the surface of B-lymphocytes.
E) in the thymus, spleen, and lymph nodes.

F) C) and D)
G) None of the above

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MHC class I molecules are


A) glycolipid synthesized on the smooth endoplasmic reticulum.
B) glycoproteins synthesized on the rough endoplasmic reticulum.
C) small peptides synthesized on free ribosomes.
D) phospholipids synthesized in secretory vesicles.

E) A) and B)
F) B) and D)

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The immunity that occurs as a result of a vaccination is ________ immunity.


A) active
B) passive

C) A) and B)
D) undefined

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Which type of lymphocyte has coreceptors that assist in the interaction of the lymphocyte with a cell presenting antigen?


A) T-lymphocyte
B) B-lymphocyte

C) A) and B)
D) undefined

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Which type of antigen would have the greatest immunogenicity?


A) One that is small, simple, familiar, and abundant
B) One that is small but complex and rare
C) One that is large, complex, foreign, and abundant
D) One that is large but simple and familiar

E) A) and B)
F) A) and C)

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Inflammation is a(n)


A) antigen-specific process that occurs in avascular tissue.
B) antigen-specific process that occurs in vascularized tissue.
C) nonspecific process that occurs in avascular tissue.
D) nonspecific process that occurs in vascularized tissue.

E) B) and D)
F) A) and B)

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