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Which affects osteoblast and osteoclast activity


A) Gravity
B) Mechanical stress
C) Calcitonin and parathyroid hormone levels
D) Blood calcium level
E) All of the choices are correct.

F) B) and D)
G) C) and E)

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The zones found in an epiphyseal plate are A: Calcified cartilage B: Hypertrophic cartilage C: Ossification D: Resting cartilage E: Proliferating cartilage The correct order for these zones,beginning with the edge closest to the epiphysis and proceeding toward the diaphysis,is


A) c - a - b - e - d
B) d - b - e - a - c
C) e - d - a - c - b
D) c - d - e - a - b
E) d - e - b - a - c

F) A) and E)
G) A) and D)

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In the kidneys,parathyroid hormone acts to ________ production of calcitriol and to ________ excretion of calcium in urine.


A) increase;increase
B) increase;decrease
C) decrease;decrease
D) decrease;increase

E) B) and D)
F) All of the above

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As the bone matrix calcifies and the secreting cells become walled in,


A) osteoblasts become osteocytes.
B) osteogenic progenitors become osteoclasts.
C) osteoblasts become osteoclasts.
D) osteoclasts become osteocytes.

E) B) and C)
F) A) and D)

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Before beginning orthodontic treatment,a patient may have her wrist and hand x-rayed to determine her stage of growth.What feature of the long bones will the orthodontist use to assess this


A) Osteon
B) Periosteum
C) Spongy bone
D) Epiphyseal plate
E) Compact bone

F) B) and E)
G) A) and E)

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D

During the process of endochondral ossification,chondrocytes in the cartilage model die.Why does this occur


A) Blood supply to the cartilage is cut off by the developing periosteum.
B) Canaliculi connecting adjacent chondrocyte lacunae fuse.
C) Nutrients cannot diffuse to the chondrocytes through the calcified matrix.
D) The developing bone collar secretes enzymes that destroy the chondrocytes.
E) Phagocytic osteoclasts in the new bone engulf and destroy the chondrocytes.

F) B) and C)
G) A) and E)

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What are the matrix rings of compact bone that surround the central canal of each osteon


A) Canaliculi
B) Concentric lamellae
C) Circumferential lamellae
D) Perforating canals
E) Interstitial lamellae

F) A) and B)
G) A) and E)

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Osteoblasts are bone-forming cells;osteoclasts are bone-dissolving cells.

A) True
B) False

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True

An osteoclast has a ruffled border and multiple nuclei.

A) True
B) False

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In adults,the medullary cavities of most long bones contain red marrow.

A) True
B) False

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Bone growth in which the bone increases in diameter is called


A) interstitial growth.
B) epiphyseal growth.
C) appositional growth.
D) endosteal growth.
E) cancellous bone growth.

F) A) and E)
G) C) and D)

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What helps bone resist compression


A) Yellow bone marrow
B) Reticular fibers
C) Inorganic salts
D) Red bone marrow
E) Endosteum

F) A) and E)
G) A) and D)

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Mechanical stress of bones,such as that caused by weight lifting,is detected by


A) osteocytes,which then communicate to osteoblasts to increase synthesis of osteoid.
B) osteoclasts,which then communicate to osteocytes to increase the size of lacunae.
C) chondrocytes,which then trigger osteoblasts to increase bone in a lengthwise fashion.
D) osteoblasts,which then communicate to osteocytes and osteoclasts to deposit more hydroxyapatite.

E) A) and B)
F) B) and C)

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When during human development does the process of ossification begin


A) 12 weeks after birth
B) 12th-13th week of embryonic development
C) 8th-9th month of fetal development
D) 3-4 months of age
E) 10-25 years of age

F) None of the above
G) A) and E)

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The shaft of a long bone is called the _________.

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diaphysis

Which hormone inhibits bone growth


A) Calcitonin
B) Estrogen and testosterone
C) Thyroid hormone
D) Parathyroid hormone
E) Growth hormone

F) A) and B)
G) A) and C)

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Spongy bone makes up less than half of total bone mass,and is located internal to compact bone.

A) True
B) False

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Which is a change in bone architecture or mass related to aging


A) Insufficient calcification
B) Demineralization
C) Reduction in the organic content of the matrix
D) Loss of flexibility and increase in brittleness
E) All of the choices are correct.

F) B) and E)
G) A) and D)

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Which is an alternate term for compact bone


A) Cancellous bone
B) Trabecular bone
C) Spongy bone
D) Diploe
E) Cortical bone

F) D) and E)
G) A) and E)

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Which is not true about bone remodeling


A) It occurs throughout life.
B) It assists in the maintenance of calcium and phosphate levels in the body.
C) It occurs at both the endosteal and periosteal surfaces of the bone.
D) It occurs only at articular surfaces.
E) It can occur in response to stress on a bone.

F) B) and E)
G) D) and E)

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