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Which of the following structures is the embryonic precursor to the human spinal cord?


A) notochord
B) neural tube
C) mesoderm
D) archenteron

E) A) and D)
F) B) and D)

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Which of the following outcomes would most likely occur if gastrulation was blocked?


A) cleavage would not occur in the zygote
B) embryonic germ layers would not form
C) the blastula would not be formed
D) the blastopore would form above the gray crescent in the animal pole

E) A) and B)
F) B) and D)

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B

In humans, identical twins are possible because ________.


A) extraembryonic cells interact with the zygote nucleus
B) convergent extension occurs
C) early blastomeres can form a complete embryo if isolated
D) the gray crescent divides the dorsal-ventral axis into new cells

E) All of the above
F) A) and B)

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Use the following information to answer the question. In an investigation into sperm-oocyte binding, researchers isolated the egg receptor protein, ERB1, from the sea urchin Strongylocentrotus purpuratus. ERB1 binds to the sperm acrosomal protein, bindin, during fertilization. The researchers coupled the ERB1 receptor from S. purpuratus to plastic microbeads and then mixed the ERB1-coupled beads with sperm from S. purpuratus or from the related species, S. franciscanus. A summary of the treatment mixtures and a graph of the results are shown. Treatments: A: S. purpuratus sperm mixed with S. purpuratus ERB1-coupled beads B: S. purpuratus sperm mixed with beads with no coupled ERB1 protein C: S. franciscanus sperm mixed with S. purpuratus ERB1 beads D: S. franciscanus sperm mixed with beads with no coupled ERB1 protein Use the following information to answer the question. In an investigation into sperm-oocyte binding, researchers isolated the egg receptor protein, ERB1, from the sea urchin Strongylocentrotus purpuratus. ERB1 binds to the sperm acrosomal protein, bindin, during fertilization. The researchers coupled the ERB1 receptor from S. purpuratus to plastic microbeads and then mixed the ERB1-coupled beads with sperm from S. purpuratus or from the related species, S. franciscanus. A summary of the treatment mixtures and a graph of the results are shown. Treatments: A: S. purpuratus sperm mixed with S. purpuratus ERB1-coupled beads B: S. purpuratus sperm mixed with beads with no coupled ERB1 protein C: S. franciscanus sperm mixed with S. purpuratus ERB1 beads D: S. franciscanus sperm mixed with beads with no coupled ERB1 protein   Based on the description of the experiment, which of the treatments would be considered a negative-control treatment for S. purpuratus sperm binding? A)  Treatment A B)  Treatment B C)  Treatment C D)  Treatment D Based on the description of the experiment, which of the treatments would be considered a negative-control treatment for S. purpuratus sperm binding?


A) Treatment A
B) Treatment B
C) Treatment C
D) Treatment D

E) A) and B)
F) None of the above

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If an egg cell were treated with EDTA, a chemical that binds calcium and magnesium ions, ________.


A) the acrosomal reaction would be blocked
B) the fusion of sperm and egg nuclei would be blocked
C) the fast block to polyspermy would not occur
D) the fertilization envelope would not form

E) A) and C)
F) B) and D)

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In sea urchins, which of the following pairs of events most directly results in the short-lasting "fast block" and the longer-lasting "slow block" to polyspermy, respectively?


A) the acrosomal reaction and vitellogenesis
B) the cortical reaction and the formation of yolk protein
C) formation of the jelly coat and the vitellin membranes
D) membrane depolarization and the cortical reaction

E) A) and D)
F) All of the above

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Cells transplanted from the neural tube of a frog embryo to the ventral part of another embryo develop into nervous system tissues. This result indicates that the transplanted cells were ________.


A) totipotent
B) determined
C) differentiated
D) mesenchymal

E) B) and D)
F) All of the above

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In addition to maternal effect genes, paternal effect genes are important for fruit fly development. One such paternal effect gene codes for Sneaky, a protein required for breakdown of the fruit fly sperm plasma membrane that is a critical step for normal embryo development. Suppose that a female fruit fly's oocyte (egg) with a mutation in the bicoid gene is fertilized by a male fruit fly's sperm with a mutation in the Sneaky gene. Both mutations yield nonfunctional proteins. What would be the most likely outcome of this fertilization?


A) a normal embryo would develop
B) an embryo would not be able to develop
C) an embryo would develop with a normal posterior end and with posterior structures on the anterior end
D) an embryo would develop with a normal anterior end and with anterior structures on the anterior end

E) A) and D)
F) None of the above

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Which of the following structures is formed before the others during frog development?


A) blastopore
B) mouth
C) blastocoel
D) anus

E) A) and B)
F) B) and C)

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What is a human embryo called at the time of implantation?


A) blastocyst
B) gastrula
C) fetus
D) zygote

E) A) and B)
F) C) and D)

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Contact between signaling molecules on a sperm membrane with receptor molecules on an oocyte membrane will most directly result in which of the following responses?


A) mitosis
B) membrane depolarization
C) vitellogenesis
D) an acrosomal reaction

E) A) and B)
F) A) and C)

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Researchers were investigating the effects of bicoid in fruit fly development. The gene bicoid controls normal development of anterior structures in flies. In one experiment, they took a normally developing embryo and injected bicoid mRNA into the posterior end of the embryo. What result would they most likely observe?


A) The embryo would develop with a normal anterior end and anterior structures on the posterior end.
B) The embryo would develop with a normal posterior end and posterior structures on the anterior end.
C) The embryo would develop with anterior structures on the posterior end and posterior structures on the anterior end.
D) The embryo would develop with a normal anterior end and a normal posterior end.

E) A) and B)
F) A) and C)

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Which of the following terms applies to a morphogenetic process whereby cells extend themselves, making the mass of the cells narrower and wider?


A) convergent extension
B) induction
C) invagination
D) involution

E) B) and C)
F) A) and B)

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A

Which of the following structures releases enzymes that initiate implantation of an embryo in the endometrium?


A) inner cell mass
B) endoderm
C) mesoderm
D) trophoblast

E) A) and B)
F) A) and C)

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D

Which of the following correctly matches a structure with the germ layer from which it is derived?


A) The mesoderm gives rise to the notochord.
B) The endoderm gives rise to the hair follicles.
C) The ectoderm gives rise to the liver.
D) The mesoderm gives rise to the lungs.

E) C) and D)
F) B) and D)

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Which of the following types of embryos displays meroblastic cleavage, extraembryonic membranes, and a primitive streak?


A) an insect
B) an amphibian
C) a bird
D) a sea urchin

E) C) and D)
F) All of the above

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During which stage of development do cells in a triploblastic embryo move to new positions to establish the three germ tissue layers?


A) determination
B) cleavage
C) induction
D) gastrulation

E) A) and C)
F) A) and B)

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Which of the following occurs to the blastocoel during frog development?


A) becomes the archenteron
B) gives rise to the endoderm
C) gives rise to the placenta
D) is replaced by the expanding archenteron

E) A) and B)
F) B) and D)

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Which of the following processes determines the arrangement of organs and tissues in their characteristic places in 3-D space?


A) pattern formation
B) differentiation
C) determination
D) organogenesis

E) None of the above
F) A) and B)

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Under which condition will the metabolic activity in a sea urchin egg most likely be activated even in the absence of sperm?


A) abnormally high levels of carbonic acid in the cytosol
B) abnormally low levels of extracellular oxygen
C) injection of calcium ions into the cytosol
D) depletion of its ATP supplies

E) A) and C)
F) All of the above

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