Question 1

Individuals with mutations in excision repair enzymes may suffer from ____ due to unrepaired DNA damage caused by ____.

Accepted Answer

A)   skin cancer; mutations inherited from their parents
B)   colon cancer; the passing of DNA mutations to daughter cells
C)   prostate cancer; telomerase
D)   skin cancer; the sun's UV rays
E)   skin cancer; complementary base pairingF) A) and D)
G) B) and E)

Question 2

How is a bacterial chromosome replicated?

Accepted Answer

A)   The linear DNA molecule is replicated from multiple origins of replication bidirectionally.
B)   The linear DNA molecule is replicated from one origin of replication bidirectionally.
C)   The circular DNA molecule is replicated from multiple origins of replication bidirectionally.
D)   The circular DNA molecule is replicated from one origin of replication bidirectionally.
E)   The circular DNA molecule is replicated from one origin of replication unidirectionally.F) C) and D)
G) B) and D)

Question 3

How are eukaryotic chromosomes replicated?

Accepted Answer

A)   The linear DNA molecules are replicated from multiple origins of replication bidirectionally.
B)   The linear DNA molecules are replicated from one origin of replication bidirectionally.
C)   The circular DNA molecules are replicated from multiple origins of replication bidirectionally.
D)   The circular DNA molecules are replicated from one origin of replication bidirectionally.
E)   The linear DNA molecules are replicated from one origin of replication unidirectionally.F) C) and E)
G) A) and C)

Question 4

Match between columns
                        Premises: produces breaks in the DNA molecules and then rejoins the strands to prevent supercoiling
prevents the hydrolysis of single DNA strands by nucleases
opens the double helix like a zipper
prevents formation of hydrogen bonds between complementary base pairs
catalyzes formation of sugar-phosphate bonds in adjacent Okazaki fragments
catalyzes a reaction that occurs in the lagging strand but not in the leading strand
adds nucleotides only to the 3' end of an existing polynucleotide strand
joins successive nucleotides to a growing polynucleotide strand, complementary to the template strand
binds DNA at the origin of replication and breaks the hydrogen bonds between the paired bases
catalyzes the synthesis of an RNA primer at both leading and lagging strand

Accepted Answer

The Answer of DNA polymerase and DNA primase and topoisomerase is...

Question 5

Why is DNA able to store large amounts of information?

Accepted Answer

A)   It is composed of 20 different nucleotides.
B)   Its nucleotides can be arranged in a large number of possible sequences.
C)   It is capable of assuming a wide variety of shapes.
D)   Its sugars and phosphates can be arranged in many different sequences.
E)   Its bases can be altered from purines to pyrimidines.F) A) and B)
G) All of the above

Question 6

In order to fit the X-ray crystallographic data, the two DNA strands must be ____ to each other.

Accepted Answer

A)   complementary
B)   uncomplementary
C)   parallel
D)   antiparallel
E)   semiconservativeF) A) and D)
G) C) and D)

Question 7

Which of the following nucleotide sequences represents the complement to the DNA strand 5 ′ − AGATCCG- 3 ′ ?

Accepted Answer

A)   5 ′ − AGATCCG- 3 ′
B)   3 ′ − AGATCCG- 5 ′
C)   5 ′ − CTCGAAT- 3 ′
D)   3 ′ − CTCGAAT- 5 ′
E)   3 ′ − TCTAGGC- 5 ′F) C) and D)
G) A) and B) E

Question 8

In DNA replication, the lagging strand:

Accepted Answer

A)   is synthesized as a series of Okazaki fragments.
B)   is synthesized as a complementary copy of the leading strand.
C)   pairs with the leading strand by complementary base pairing.
D)   is made up entirely of RNA primers.
E)   is not synthesized until the synthesis of the leading strand is completed.F) A) and E)
G) A) and D)

Question 9

List the steps and components involved in the process of DNA replication.

Accepted Answer

The general process of DNA rep...

Question 10

Single-strand binding proteins prevent the hydrolysis of single-strand regions of DNA by nucleases. 
__________________

Accepted Answer

A) True 
 B)False  True

Question 11

What is meant by the "directionality" of the strands of a DNA molecule? Explain how this directionality is ultimately responsible for Okazaki fragments.

Accepted Answer

Concepts to Consider: The anti...

Question 12

The two strands of a DNA double helix can be described as running parallel to each other. 
__________________

Accepted Answer

A) True 
 B)False

Question 13

Who first confirmed that the replication of DNA was semiconservative?

Accepted Answer

A)   Chargaff and Hershey
B)   Watson and Crick
C)   Avery and Griffith
D)   Meselson and Stahl
E)   Watson, Crick, and WilkinsF) None of the above
G) C) and E)

Question 14

Provide two lines of evidence that support the idea that DNA is the genetic material.

Accepted Answer

Concepts to Consider: The experiments of...

Question 15

When a mutation occurs during DNA replication, ____ replaces the incorrect nucleotide with the correct one after the mismatched nucleotide has been removed.

Accepted Answer

A)   mismatch repair enzymes
B)   DNA ligase
C)   DNA polymerase
D)   telomerase
E)   helicaseF) A) and D)
G) A) and C)

Question 16

Primase is the enzyme responsible for:

Accepted Answer

A)   unwinding the DNA double strand to allow DNA polymerase access to the template DNA.
B)   introducing nicks into the DNA double strand in order to prevent the formation of knots.
C)   hydrolyzing ATP to facilitate DNA unwinding.
D)   making short strands of RNA at the site of replication initiation.
E)   forming a replication fork in the DNA double helix.F) A) and B)
G) C) and D)

Question 17

The DNA strand that is replicated smoothly and continuously is called the:

Accepted Answer

A)   primary strand.
B)   template strand.
C)   leading strand.
D)   Okazaki fragment.
E)   lagging strand.F) C) and D)
G) A) and D)

Question 18

DNA synthesis:

Accepted Answer

A)   is unidirectional.
B)   is facilitated by a phosphodiester linkage.
C)   occurs only once during each cell generation.
D)   has few mechanisms for fixing errors.
E)   is proofread by DNA ligase.F) A) and D)
G) A) and B)

Question 19

A replication fork is:

Accepted Answer

A)   observed only in prokaryotic chromosomes.
B)   observed only in nondividing cells..
C)   a Y-shaped structure where parental DNA strands are separated by helicase.
D)   a site where one DNA strand serves as a template, but the other strand is not replicated.
E)   created by the action of the enzyme RNA polymerase.F) A) and D)
G) A) and C) C

Question 20

The information encoded by the DNA is specified by the:

Accepted Answer

A)   sugar-phosphate backbone of the DNA molecule.
B)   number of separate DNA strands.
C)   size of a particular chromosome.
D)   nucleotide sequence of the DNA molecule.
E)   number of bases in a DNA molecule.F) A) and C)
G) A) and B)

Exam 12: Dna the Carrier of Genetic Information

Individuals with mutations in excision repair enzymes may suffer from due to unrepaired DNA damage caused by .

Correct Answer
verified

How is a bacterial chromosome replicated?

Correct Answer
verified

How are eukaryotic chromosomes replicated?

Correct Answer
verified

In the following questions, match the component of DNA replication with its function.

Why is DNA able to store large amounts of information?

Correct Answer
verified

In order to fit the X-ray crystallographic data, the two DNA strands must be ____ to each other.

Correct Answer
verified

Which of the following nucleotide sequences represents the complement to the DNA strand 5 ′ − AGATCCG- 3 ′ ?

Correct Answer
verified
E

In DNA replication, the lagging strand:

Correct Answer
verified

List the steps and components involved in the process of DNA replication.

Correct Answer
verified
The general process of DNA rep...
View Answer

Single-strand binding proteins prevent the hydrolysis of single-strand regions of DNA by nucleases. __________________

Correct Answer
verified
True

What is meant by the "directionality" of the strands of a DNA molecule? Explain how this directionality is ultimately responsible for Okazaki fragments.

Correct Answer
verified
Concepts to Consider: The anti...
View Answer

The two strands of a DNA double helix can be described as running parallel to each other. __________________

Correct Answer
verified

Who first confirmed that the replication of DNA was semiconservative?

Correct Answer
verified

Provide two lines of evidence that support the idea that DNA is the genetic material.

Correct Answer
verified
Concepts to Consider: The experiments of...
View Answer

When a mutation occurs during DNA replication, ____ replaces the incorrect nucleotide with the correct one after the mismatched nucleotide has been removed.

Correct Answer
verified

Primase is the enzyme responsible for:

Correct Answer
verified

The DNA strand that is replicated smoothly and continuously is called the:

Correct Answer
verified

DNA synthesis:

Correct Answer
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A replication fork is:

Correct Answer
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C

The information encoded by the DNA is specified by the:

Correct Answer
verified

Exam 12: Dna the Carrier of Genetic Information

Individuals with mutations in excision repair enzymes may suffer from ____ due to unrepaired DNA damage caused by ____.

Correct AnswerverifiedShow Answer

How is a bacterial chromosome replicated?

Correct AnswerverifiedShow Answer

How are eukaryotic chromosomes replicated?

Correct AnswerverifiedShow Answer

In the following questions, match the component of DNA replication with its function.

Why is DNA able to store large amounts of information?

Correct AnswerverifiedShow Answer

In order to fit the X-ray crystallographic data, the two DNA strands must be ____ to each other.

Correct AnswerverifiedShow Answer

Which of the following nucleotide sequences represents the complement to the DNA strand 5 ′ − AGATCCG- 3 ′ ?

Correct AnswerverifiedE

In DNA replication, the lagging strand:

Correct AnswerverifiedShow Answer

List the steps and components involved in the process of DNA replication.

Correct AnswerverifiedThe general process of DNA rep...View AnswerShow Answer

Single-strand binding proteins prevent the hydrolysis of single-strand regions of DNA by nucleases. __________________

Correct AnswerverifiedTrue

What is meant by the "directionality" of the strands of a DNA molecule? Explain how this directionality is ultimately responsible for Okazaki fragments.

Correct AnswerverifiedConcepts to Consider: The anti...View AnswerShow Answer

The two strands of a DNA double helix can be described as running parallel to each other. __________________

Correct AnswerverifiedShow Answer

Who first confirmed that the replication of DNA was semiconservative?

Correct AnswerverifiedShow Answer

Provide two lines of evidence that support the idea that DNA is the genetic material.

Correct AnswerverifiedConcepts to Consider: The experiments of...View AnswerShow Answer

When a mutation occurs during DNA replication, ____ replaces the incorrect nucleotide with the correct one after the mismatched nucleotide has been removed.

Correct AnswerverifiedShow Answer

Primase is the enzyme responsible for:

Correct AnswerverifiedShow Answer

The DNA strand that is replicated smoothly and continuously is called the:

Correct AnswerverifiedShow Answer

DNA synthesis:

Correct AnswerverifiedShow Answer

A replication fork is:

Correct AnswerverifiedC

The information encoded by the DNA is specified by the:

Correct AnswerverifiedShow Answer

Individuals with mutations in excision repair enzymes may suffer from due to unrepaired DNA damage caused by .

Correct Answer
verified

Correct Answer
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Correct Answer
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E

Correct Answer
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The general process of DNA rep...
View Answer

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True

Correct Answer
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Concepts to Consider: The anti...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
Concepts to Consider: The experiments of...
View Answer

Correct Answer
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Correct Answer
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Correct Answer
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Correct Answer
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Correct Answer
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C

Correct Answer
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