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Which immunoglobulin is present in blood, saliva, breast milk, and respiratory secretions?


A) IgA
B) IgE
C) IgG
D) IgM

E) A) and B)
F) C) and D)

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Cytokines are vital to a cell's ability to do which function?


A) Excrete
B) Reproduce
C) Metabolize
D) Communicate

E) All of the above
F) C) and D)

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Which is an example of a bacterial toxin that has been inactivated but still retains its immunogenicity to protect the person? (Select all that apply.)


A) Poliomyelitis
B) Measles
C) Tetanus
D) Gonorrhea
E) Diphtheria

F) B) and D)
G) B) and C)

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Which statements are true concerning the humoral immune response? (Select all that apply.)


A) The humoral immune response is divided into major and minor phases.
B) The response has IgG and IgM produced during each of its phrases.
C) It has a greater presence of IgG than IgM in one of its phases.
D) The humoral immune response is produced in reaction to the presence of an antigen.
E) Phases differ in their response time as a result of the effect of memory cells.

F) C) and E)
G) B) and C)

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Which T cell controls or limits the immune response to protect the host's own tissues against an autoimmune response?


A) Cytotoxic T cells
B) Th1 cells
C) Th2 cells
D) Regulatory T (Treg) cells

E) B) and C)
F) None of the above

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How do antibodies protect the host from bacterial toxins?


A) Lysing the cell membrane of the toxins
B) Binding to the toxins to neutralize their biologic effects
C) Inhibiting the synthesis of DNA proteins needed for growth
D) Interfering with the DNA enzyme needed for replication

E) A) and B)
F) C) and D)

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Which antibody initially indicates a typical primary immune response?


A) IgG
B) IgM
C) IgA
D) IgE

E) None of the above
F) A) and D)

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Antibodies that are associated with mucosal immune system, such as immunoglobulins, function to prevent which type of infections?


A) Infections that attack the respiratory system
B) Infections that tend to be chronic in nature
C) Infections likely to be resistant to antibiotics
D) Infections that focus on epithelial surfaces of the body

E) All of the above
F) C) and D)

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Which type of immunity is produced by an individual after either natural exposure to the antigen or after immunization against the antigen?


A) Passive-acquired immunity
B) Active-acquired immunity
C) Passive-innate immunity
D) Active-innate immunity

E) A) and D)
F) A) and C)

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Which statement is true regarding maternal antibodies provided to the neonate?


A) The antibodies enter into the fetal circulation by means of active transport.
B) The antibodies are transferred to the fetus via the lymphatic system.
C) The antibodies are directly related to the mother's nutritional intake.
D) The antibodies reach protective levels after approximately 6 months of age.

E) A) and D)
F) A) and C)

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A

Th2 cells produce IL-4 and suppress which cells?


A) B lymphocytes
B) Cytotoxic T lymphocytes
C) Th1 cells
D) Memory T lymphocytes

E) A) and B)
F) A) and C)

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C

Which is an example of an endogenous antigen?


A) Yeast
B) Cancer cells
C) Bacteria
D) Fungus

E) A) and B)
F) None of the above

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What type of immunity is produced when an immunoglobulin crosses the placenta?


A) Passive-acquired immunity
B) Active-acquired immunity
C) Passive-innate immunity
D) Active-innate immunity

E) C) and D)
F) A) and C)

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Vaccinations are able to provide protection against certain microorganisms because of what?


A) Strong response from IgM
B) Level of protection provided by IgG
C) Memory cells for IgE
D) Rapid response from IgA

E) A) and B)
F) C) and D)

Correct Answer

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Where are antibodies produced?


A) Helper T lymphocytes
B) Thymus gland
C) Plasma cells
D) Bone marrow

E) B) and C)
F) A) and B)

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C

What is the term for the process during which lymphoid stem cells migrate and change into either immunocompetent T cells or immunocompetent B cells?


A) Clonal diversity
B) Clonal differentiation
C) Clonal selection
D) Clonal competence

E) All of the above
F) B) and C)

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CD4 is a characteristic surface marker and a result of which of these? (Select all that apply.)


A) Activity in the primary lymphoid organs
B) Process of cellular differentiation
C) Alterations to T cells
D) Changes to B cells
E) Clonal selection

F) C) and E)
G) All of the above

Correct Answer

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The functions of the major histocompatibility complex (MHC) and CD1 molecules are alike because both do what?


A) Are antigen-presenting molecules
B) Bind antigens to antibodies
C) Secrete interleukins during the immune process
D) Are capable of activating cytotoxic T lymphocytes

E) A) and B)
F) C) and D)

Correct Answer

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Evaluation of umbilical cord blood can confirm that which immunoglobulin level is near adult levels?


A) IgA
B) IgG
C) IgM
D) IgE

E) A) and D)
F) C) and D)

Correct Answer

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The generation of clonal diversity occurs primarily during which phase of life?


A) Fetal
B) Neonatal
C) Infancy
D) Puberty

E) B) and C)
F) A) and D)

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