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Which of the following statement are true regarding the use of hyperventilation in the management of patients with TBI? I.Hyperventilation is effective for only about 24 to 48 hours. II.Hyperventilating patients with TBI to a PaCO2 less than 30 mm Hg increases the danger of cerebral ischemia. III.Every patient with TBI should be hyperventilated, at least during the first 24 hours. IV.Hyperventilation therapy should be considered only for patients with high ICPs.


A) II, III, IV
B) I, II, III, IV
C) II, IV
D) I, II, IV

E) All of the above
F) C) and D)

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Which of the following reflexes may be involved in periodic deep sighs and stimulating the first breaths of a newborn baby?


A) Hering-Breuer reflex
B) Head's reflex
C) Stretch reflex
D) Bötzinger reflex

E) All of the above
F) A) and C)

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Which of the following statements describes apneusis?


A) Prolonged inspiratory gasps interrupted by occasional expirations
B) Prolonged inspiratory gasps interrupted by apnea
C) Prolonged inspiratory gasps interrupted by frequent expirations
D) Short inspiratory gasps interrupted by occasional expirations

E) A) and C)
F) B) and C)

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Why are COPD patients with chronic hypercapnia unable to hyperventilate to decrease their PaCO2?


A) The central chemoreceptors respond only to O2 concentration changes, not to changes in CO2.
B) The central chemoreceptors are insensitive to acute or chronic changes in PaCO2.
C) The central chemoreceptors respond to [H+], not the CO2 molecule.
D) The central chemoreceptors do not respond to changes in hydrogen ion concentration or PaCO2.

E) B) and C)
F) B) and D)

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Which of the following describes Biot's breathing?


A) Tidal volume gradually increases and then gradually decreases to complete apnea without changes in respiratory rate. Then the tidal volume gradually increases again.
B) The respiratory rate and tidal volume gradually increase and then gradually decrease to complete apnea. Then the tidal volume and breathing frequency gradually increase again.
C) The respiratory rate gradually increases and then gradually decreases to complete apnea but tidal volume has essentially the same depth. Then the breathing frequency gradually increases again.
D) Tidal volume gradually decreases to complete apnea. Then the tidal volume gradually increases again, repeating the cycle.

E) None of the above
F) B) and D)

Correct Answer

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How much does minute ventilation increase for each 1 mm Hg rise in PaCO2?


A) 1 to 2 L/min
B) 2 to 3 L/min
C) 4 to 5 L/min
D) 5 to 6 L/min

E) C) and D)
F) B) and D)

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Which of the following respiratory centers controls the length of inspiration?


A) DRG
B) VRG
C) Pneumotaxic
D) Apneustic

E) None of the above
F) A) and C)

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What is the explanation for the minor importance of oxygen in controlling ventilation?


A) Oxygen molecules compete with CO2 levels.
B) Oxygen molecules are fewer than CO2 molecules.
C) Oxygen molecules do not cross the blood-brain barrier.
D) Oxygen molecules have no effect on the medullary chemoreceptors.

E) C) and D)
F) All of the above

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Which of the following events are feasible explanations for the oxygen-associated hypercapnia that sometimes affects patients who have severe COPD? I.Hypoxic stimulus removal II.Worsening of V˙/Q˙\dot{V} / \dot{Q} relationships III.As PaO2 increases, the slow reduction in PaCO2 induces hypoventilation. IV.Shunt


A) II, III, IV
B) I, II, III, IV
C) II, IV
D) I, II

E) B) and C)
F) A) and B)

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Which of the following statements are true of the peripheral chemoreceptors? I.They account for only 20% to 30% of the ventilatory response to hypercapnia. II.Unlike the central chemoreceptors, the carotid bodies are directly exposed to arterial blood. III.The initial ventilatory response to metabolic acidosis is fairly quick. IV.They are the most important mechanisms that respond to hypercapnia.


A) II, III, IV
B) I, II, III, IV
C) II, IV
D) I, II, III

E) B) and C)
F) None of the above

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Which of the following conditions produces the strongest stimulation of the J-receptors?


A) Pneumonia
B) Pneumothorax
C) Pleural effusion
D) Lung cancer

E) A) and B)
F) C) and D)

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Which of the following conditions stimulate the chemoreceptors? I.Hypercapnia II.Acidemia III.Hypoxia IV.Alkalemia


A) I, II
B) III, IV
C) I, II, III
D) II, III, IV

E) B) and C)
F) A) and D)

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What is the clinical importance of the periodic deep sighs during quiet breathing?


A) Help prevent alveolar collapse or atelectasis
B) Maintain the normal breathing pattern
C) Help prevent apneustic breathing patterns
D) Promote coughing

E) None of the above
F) A) and B)

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Which of the following mechanisms explains ventilatory stimulation caused by hypoxemia in COPD patients with moderate hypoxemia?


A) Hypoxemia raises the peripheral chemoreceptors' sensitivity to [H+].
B) Hypoxemia stimulates central chemoreceptors.
C) Hypoxemia raises the central chemoreceptors' sensitivity to [H+].
D) Hypoxemia raises the peripheral chemoreceptors' sensitivity to [CO2].

E) A) and C)
F) A) and D)

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Which of the following patterns describes Cheyne-Stokes breathing?


A) Tidal volume gradually increases and then gradually decreases to complete apnea without changes in respiratory rate. Then the tidal volume gradually increases again.
B) Respiratory rate and tidal volume gradually increase and then gradually decrease to complete apnea. Then the tidal volume and breathing frequency gradually increase again.
C) The respiratory rate gradually increases and then gradually decreases to complete apnea but tidal volume has essentially the same depth. Then the breathing frequency gradually increases again.
D) Tidal volume gradually decreases to complete apnea. Then the tidal volume gradually increases again, repeating the cycle.

E) B) and D)
F) All of the above

Correct Answer

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